COMPLEMENT C5A INDUCES THE GENERATION OF NEUTROPHIL EXTRACELLULAR TRAPS BY INHIBITING MITOCHONDRIAL STAT3 TO PROMOTE THE DEVELOPMENT OF ARTERIAL THROMBOSIS

Abstract Background Thrombotic events cannot be completely prevented by antithrombotics, implicating a therapeutic gap due to inflammation, a not yet sufficiently addressed mechanism.Neutrophil extracellular traps (NETs) are an essential interface between inflammation and thrombosis, but exactly jumbo tuz de?irmeni how the NETotic process is initia

This study explores in detail the functional consequences of subtle retraction and detachment of myelin around the nodes of Ranvier following mild-to-moderate crush or stretch mediated injury.An equivalent electrical circuit model for a series of equally spaced nodes of Ranvier was created incorporating extracellular and axonal resistances, paranod

ObjectivesIn response to the increasing depth of research and design on liquefied natural gas (LNG) ship structures, higher requirements are put forward for a reliability analysis method that can quickly and accurately evaluate uncertain factors.This paper proposes a method based on human after all vinyl an improved random forest-Monte Carlo method

ABSTRACT Objective: To identify the factors associated with Upright Delivery (UD) performed in hospitals linked to the Rede Cegonha (RC) in Brazil.Methods: Cross-sectional study with 3,073 parturients who had vaginal delivery in 606 health facilities in Brazil, located in health regions with a regional action plan approved in the RC.Socioeconomic,